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Aleksandra Zivkovic Selected Research

Fingolimod Hydrochloride (FTY720)

1/2021Novel compounds with dual S1P receptor agonist and histamine H3 receptor antagonist activities act protective in a mouse model of multiple sclerosis.
9/2020Morpholino Analogues of Fingolimod as Novel and Selective S1P1 Ligands with In Vivo Efficacy in a Mouse Model of Experimental Antigen-Induced Encephalomyelitis.
1/2016Sphingosine kinase 2 deficient mice exhibit reduced experimental autoimmune encephalomyelitis: Resistance to FTY720 but not ST-968 treatments.
6/2015Antinociceptive effects of FTY720 during trauma-induced neuropathic pain are mediated by spinal S1P receptors.
10/2014Novel oxazolo-oxazole derivatives of FTY720 reduce endothelial cell permeability, immune cell chemotaxis and symptoms of experimental autoimmune encephalomyelitis in mice.

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Aleksandra Zivkovic Research Topics

Disease

5Neoplasms (Cancer)
09/2023 - 02/2012
3Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
01/2021 - 10/2014
2Hematologic Neoplasms (Hematological Malignancy)
01/2022 - 05/2017
2Inflammation (Inflammations)
01/2022 - 05/2017
2Graft vs Host Disease (Graft-Versus-Host Disease)
01/2022 - 05/2017
2Neurodegenerative Diseases (Neurodegenerative Disease)
12/2021 - 03/2018
2Multiple Sclerosis
01/2021 - 10/2014
2Autoimmune Diseases (Autoimmune Disease)
09/2020 - 10/2014
2Pain (Aches)
04/2020 - 06/2015
2Relapsing-Remitting Multiple Sclerosis
01/2016 - 10/2014
1Breast Neoplasms (Breast Cancer)
01/2022
1Leukemia
01/2022
1Cognitive Dysfunction
01/2021
1Narcolepsy
01/2021
1Encephalomyelitis (Myeloencephalitis)
09/2020
1Asthma (Bronchial Asthma)
04/2020
1Obesity
04/2020
1Parkinson Disease (Parkinson's Disease)
03/2018
1Metabolic Diseases (Metabolic Disease)
08/2015
1Wounds and Injuries (Trauma)
06/2015
1Neuralgia (Stump Neuralgia)
06/2015
1Myocardial Stunning (Stunned Myocardium)
07/2013
1Takotsubo Cardiomyopathy
07/2013
1Heart Arrest (Cardiac Arrest)
07/2013

Drug/Important Bio-Agent (IBA)

5Fingolimod Hydrochloride (FTY720)FDA Link
01/2021 - 10/2014
3CeramidesIBA
09/2023 - 02/2012
3LigandsIBA
09/2020 - 03/2018
2dihydroceramide desaturaseIBA
09/2023 - 01/2022
2Histamine H3 Receptors (Histamine H3 Receptor)IBA
12/2021 - 01/2021
2Sphingosine-1-Phosphate ReceptorsIBA
01/2021 - 06/2015
27a- (4- octylphenethyl)tetrahydro- 1H- oxazolo(3,4- c)oxazoleIBA
01/2016 - 10/2014
1Biomarkers (Surrogate Marker)IBA
09/2023
1LipidsIBA
09/2023
1Hydroxychloroquine (Plaquenil)FDA LinkGeneric
01/2023
1EnzymesIBA
01/2023
1eliglustatIBA
01/2023
1Ether (Diethyl Ether)IBA
01/2022
1c-Mer Tyrosine KinaseIBA
01/2022
1CDPdiacylglycerol-Serine O-PhosphatidyltransferaseIBA
01/2022
1PhosphatidylserinesIBA
01/2022
1pitolisantIBA
01/2021
1Histamine (Histamine Dihydrochloride)FDA Link
01/2021
1piperidineIBA
01/2021
1sphingosine 1-phosphate (sphingosine-1-phosphate)IBA
01/2021
1AntigensIBA
09/2020
1siponimodIBA
09/2020
1MorpholinosIBA
09/2020
1imidazoleIBA
04/2020
1indacrinoneIBA
03/2018
1Monoamine Oxidase (MAO)IBA
03/2018
1sphingosine kinaseIBA
01/2016
1ResveratrolIBA
08/2015
1TubulinIBA
08/2015
1FTY 720PIBA
06/2015
1Paclitaxel (Taxol)FDA LinkGeneric
06/2015
1OxazolesIBA
10/2014
17a- (4- (heptyloxy)phenethyl)tetrahydro- 1H- oxazolo(3,4- c)oxazoleIBA
10/2014

Therapy/Procedure

3Therapeutics
09/2023 - 10/2014
2Immunotherapy
01/2022 - 05/2017
2Cell Transplantation
01/2022 - 05/2017
1Drug Therapy (Chemotherapy)
06/2015
1General Anesthesia
07/2013